B.1.617

Translingual

Alternative forms

• B-1-617

Proper noun

B.1.617

1. (virology) A virulent variant of the SARS-CoV-2 Coronavirus, which causes COVID-19; that has two significant mutations, E484Q and L452R, causing a wave of new infections in India in Spring 2021.
   • 2023, Laiali Alquraan, Karem H. Alzoubi, Suzie Y. Rababa'h, “Mutations of SARS-CoV-2 and their impact on disease diagnosis and severity”, in Informatics in medicine unlocked, →DOI:

     The dynamics, molecular interactions, and binding energy of the B.1.1.7 variant (spike N501Y mutant), B.1.617 variant (E484Q and L452R spike mutant), and wild-type (WT) were investigated recently in India using molecular dynamics simulations of three diverse spike-ACE2 complexes.

2. (by extension) Synonym of B.1.617+, the group of sublineages derived from B.1.617 inclusive
   • 2023, Laiali Alquraan, Karem H. Alzoubi, Suzie Y. Rababa'h, “Mutations of SARS-CoV-2 and their impact on disease diagnosis and severity”, in Informatics in medicine unlocked, →DOI:

     Numerous variations of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), including D614G, B.1.1.7 (United Kingdom), B.1.1.28 (Brazil P1, P2), CAL.20C (Southern California), B.1.351 (South Africa), B.1.617 (B.1.617.1 Kappa & Delta B.1.617.2) and B.1.1.529, have been reported worldwide.

Synonyms

• G/452R.V3
• VOC-21APR
• VUI-21APR

 

Hypernyms

virus

• B.1.617+
• Coronavirus
• CoV
• SARS-CoV-2
• SARSr-CoV
• Virus

 

Hyponyms

• B.1.617 (the original variant lineage)
• B.1.617.1
• B.1.617.2 (the sublineage prominent in the UK from early 2021)
• B.1.617.3 (the first isolated variant sublineage)
• VOC-21APR-02
• VUI-21APR-01
• VUI-21APR-02
• VUI-21APR-03

 

Coordinate terms

(virus): (viral components)

• E484Q (mutant E484)
• L452R (mutant L452)
• Q484
• R452

Derived terms

• B.1.617+
• B.1.617.1
• B.1.617.2
• B.1.617.3

 

Related terms

virus

• B.1.1.248 (Brazilian precursor strain to P.1 and P.2)
• B.1.1.28 (Brazilian parent strain to P.1 and P.2)
• B.1.1.28.1 ("P.1" Manaus [Brazil] variant)
• B.1.1.28.2 ("P.2" Rio de Janeiro variant)
• B.1.1.7 (Kent [UK, British] variant)
• B.1.351 (South African variant)

 

Descendants

• English: lineage B.1.617
• English: B.1.617 lineage

Translations

Translations

• English: Indian variant, India variant, double mutant variant, double mutation variant
• Finnish: Intian muunnos, Intian virusmuunnos, Intian variantti, tuplamuunnos

Further reading

• B.1.617 on Wikipedia.Wikipedia